Master of Science in Clinical Research

Physician reviewing patient specimen under microscope
Ling-Lun Hsia, M.D., reviews a patient specimen under the microscope. Photo by Brennan Wesley.

The Master of Science in Clinical Research (MSCR) program provides rigorous, interdisciplinary training to prepare health professionals and scientists for careers in clinical and translational research. Designed for individuals with a background in medicine, pharmacy, nursing, dentistry, or related fields, this program builds core competencies in clinical trial design, biostatistics, regulatory science, and evidence-based medicine. Whether your goal is to become a principal investigator, clinical scientist, or research coordinator, MUSC's MSCR program provides the academic foundation and practical experience to lead in today's research-intensive environments.

Our curriculum is structured to accommodate the demands of working professionals while maintaining academic depth and integrity. Students benefit from a flexible learning format that includes both didactic and applied components, allowing them to balance clinical, research, or administrative responsibilities while progressing through the program. The MSCR program provides students with mentored research experiences, allowing them to work closely with MUSC's esteemed faculty, who actively conduct clinical research in various fields, including Cancer, Cardiovascular health, Digestive Diseases, Precision Medicine, and Neuroscience.

Graduates of the program leave with the skills to design and conduct independent research, contribute to multidisciplinary research teams, and translate clinical findings into improved patient outcomes. Our students actively navigate the ethical, regulatory, and methodological complexities of clinical research as they pursue careers in academia, industry, or healthcare. By training the next generation of clinical investigators, MUSC is advancing its mission to improve health through discovery and innovation.

Learning Objectives

At the end of the program, students should be able to:

  1. Conduct a comprehensive and systematic review of the literature
  2. Formulate a well-defined clinical or translational research question
  3. Select an appropriate study design to address a clinical or translational research question
  4. Compute, describe, and evaluate descriptive and inferential statistics appropriate to the chosen study design
  5. Apply ethical codes and professional standards for the conduct of clinical and translational research

Curriculum

Students can complete the part-time program in two years on a part-time basis, beginning each fall. Individuals admitted to this program complete a 38-academic credit hour master's program composed of classroom lectures and seminars.

Year 1, Fall

MCR 700 Clinical Biostatistics 3
MCR 736 Clinical Epidemiology 3
MCR 750 Ethical Issues in Clinical Research 1
MCR 770 Contemporary Topic Seminar 1
Semester Total 8

Year 1, Spring

MCR 724 Introduction to Clinical Trials 3
MCR 746 Informatics & Data Management 2
MCR 752 Team Science in Clinical Research 1
MCR 771 Regression Analysis 2
Semester Total 8

Year 1, Summer

MCR 731 Critical Review 2
MCR 772 Community Engaged Research 1
MCR 773 Industry/Regulatory 2
MCR 774 Leadership 2
MCR 970 Mentored Research 1
Semester Total 8

Year 2, Fall

MCR 725 Grant Development 2
MCR 732 Comparative Effectiveness Research 3
MCR 789 Special Topics 1
MCR 970 Mentored Research 2
Semester Total 8

Year 2, Spring

MCR 776 Innovation in Clinical Research 1
MCR 970 Mentored Research 5
Semester Total 6
Curriculum Total 38

The full-time program is designed for students who are currently pursuing doctoral degrees in one of the six colleges (Dental Medicine, Graduate Studies, Health Professions, Medicine, Nursing, and Pharmacy) as well as international applicants. Students complete the program in one year on a full-time basis.

Year 1, Fall

MCR 700 Clinical Biostatistics 3
MCR 731 Critical Review 2
MCR 736 Clinical Epidemiology 3
MCR 750 Ethical Issues in Clinical Research 1
MCR 770 Contemporary Topic Seminar 1
MCR 775 Clinical Research Training 1
MCR 970 Mentored Research 2
Semester Total 13

Year 1, Spring

MCR 724 Introduction to Clinical Trials 3
MCR 732 Comparative Effectiveness Research 3
MCR 746 Informatics & Data Management 2
MCR 752 Team Science in Clinical Research 1
MCR 771 Regression Analysis 2
MCR 777 Introduction to Grant Writing 1
MCR 970 Mentored Research 3
Semester Total 15

Year 1, Summer

MCR 772 Community Engagement Research 1
MCR 773 Industry/Regulatory 2
MCR 774 Leadership 2
MCR 789 Special Topics 1
MCR 970 Mentored Research 4
Semester Total 10
Curriculum Total 38

Approved Electives

  • IP 738
  • ETH 738
  • MCR 777. Introduction to Grant Writing (part-time only), 1 credit hour

Application Process

All applications to the College of Graduate Studies are submitted online. If you are unable to apply online, a petition to the Office of the Dean with an explanation must be submitted for special accommodation.

In addition to the application itself the applicant must complete supplemental instruction materials specific to the program to which they are applying. These forms are provided via email once an application has been submitted (and are listed under Application Materials through program links above).

Application Information

Application Materials

  1. Academic transcripts from the institution of the highest degree, as well as any professional certifications that indicate the applicant has either of the following:
    • A doctoral degree from an accredited institution in the health/clinical sciences (e.g., M.D., PharmD, O.D., D.M.D., Ph.D.)
    • A graduate or bachelor's degree in the healthcare or clinical sciences from an accredited institution of higher education (e.g., BSN, MHS)
  2. A one-two page essay that inclues:
    • Future professional goals,
    • Purpose statement for why you're applying to this program,
    • Area of research interest and qualifications, and
    • An acknowledgement, upon acceptance, that you will commit to all scheduled classes.
  3. For residents, fellows, and faculty, a letter of support stating the department guarantees the applicant will have protected time to commit to the program
    • From the residency director for residents
    • From the fellowship director for fellows
    • From the division/department chair for faculty

Complete the applications and submit admission materials online. If you are unable to apply you must petition the College of Graduate Studies Office of the Dean for special accommodations with an explanation of why you are unable to apply online. In addition to the application, supplemental instruction materials specific to each program is also uploaded. These forms are provided via email once an application has been submitted and are listed above under Application Materials.

Application Requirements

Part-Time

Candidates in this program will be individuals with a science background, specialists, residents, fellows and other healthcare professionals who seek to advance their clinical research skills and must possess:

  • A bachelor's or a master's degree in the health/clinical sciences from an accredited institution of higher education (e.g., BSN, MHS)
  • A doctoral degree from an accredited school in the health/clinical sciences (e.g., M.D., Pharm.D., O.D., D.M.D., Ph.D.)

Full-Time

For admission, a candidate must possess an undergraduate degree or graduate degree in clinical or health sciences from a U.S. accredited institution of higher education (e.g. BSN, MHS). International applicants must have a degree equivalent to a U.S. four-year baccalaureate degree from an officially recognized institution and a letter of recommendation or support letter.

Application Timeline

Part-Time

Start Term Application Type Available Deadline
Fall 2025
Priority September 1, 2024 June 19, 2025
Fall 2025
Regular Jun 20, 2025 Aug 11, 2025
Fall 2026  Priority September 1, 2025 June 19, 2026
Fall 2026  Regular June 20, 2026 Aug 1, 2026

Full-Time

Start Term Application Type Available Deadline
Fall 2025
Priority September 1, 2024 Jun 19, 2025
Fall 2025
Regular June 20, 2025 Aug 11, 2025
Fall 2026  Priority September 1, 2025 June 19, 2026 
Fall 2026  Regular June 20, 2026 Aug 1, 2026 

Scholarship Eligibility

MUSC offers scholarships for which you may be eligible. Some are awarded based on academic achievement; others are awarded based on community service, for example. However, the majority of scholarships awarded at MUSC are based on financial need. This means those scholarships are only awarded to students who need some financial assistance to cover the cost of tuition and fees. If you would like to be considered for a financial need-based scholarship, you must have an up-to-date Free Application for Federal Student Aid (FAFSA) on file. Make sure you list Medical University of South Carolina on your FAFSA form, along with MUSC's code: 003438. We encourage you to submit the FAFSA as early as possible. It is recommended to submit the FAFSA in January if you plan to enroll in the Fall.

International Students

Foreign nationals are urged to submit complete information as early as possible. In addition to other official entrance credentials, applicants whose native language is not English must submit the official results of the Test of English as a Foreign Language (TOEFL or IELTS score). The TOEFL or IELTS score must not be more than two years old. Final consideration cannot be granted to an international application for admission until the official scores are received by the Office of Enrollment Management.

If an international applicant has graduated or will graduate from an institution that uses English as the language of instruction, the TOEFL may be waived upon request.

Tuition & Fees

Explore the cost of your education and available financial options.